Langerhans cell histiocytosis: a rare cause of cholestasis in adult patients. Case report. Histiocitosis de Langerhans: causa infrecuente de colestasis en el. a Unidad Médico-Quirúrgica de Enfermedades Respiratorias. Área de Neumopatías Intersticiales y Ocupacionales. Hospital Universitario Virgen del Rocío. Abstract. GOMEZ, ANA MARÍA et al. Langerhans cell histiocytosis in children. A description of 10 cases. CES Med. [online]. , vol, n.2, pp
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All manuscripts are sent to peer-review and handled by the Editor or an Associate Editor from the team. In the case histiocjtosis multi-systemic involvement, the best results seem to be obtained with prednisone and vinblastine for months.
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Three histological patterns have been described: An ultrastructural study by transmission electron microscopy reveals the presence of Birbeck granules, although the most widely-used technique to reach a diagnosis is immunohistochemistry Langerhans cells are positive for staining with S, DC68 and CD1a. Vidal Serrano aE. Go to the members area of the website of the AEDV, https: Ann Thoracic Surg, 30pp.
Histiocitosis de células de Langerhans en niños. Descripción de 10 casos
Accumulations of histiocytes are normally accompanied by fibrosis and a chronic inflammatory with a remarkable number of eosinophils 4,5. Solitary congenital self-healing Langerhans cells histiocytosis. Discussion There are two patterns of involvement: Dear Editor, We present a 42 uistiocitosis old man, with a history of central diabetes insipidus since childhood, primary hyperthyroidism with negative antibodies and seizures since early adulthood.
After the diagnosis of Langerhans cell histiocytosis in the skin biopsy, the liver biopsy simple was reviewed and histological sections were taken from the piece of pancreas. CiteScore measures average citations received per document published. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.
Of the 10 patients 5 had risk organ involvement and 1 died in the observation period. CiteScore measures average citations received per document published.
See more Access to any published article, in either language, is possible through the Journal web page as well as from Pubmed, Science Direct, and other international databases. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. Previous article Next article. Are you a health professional able to prescribe or dispense drugs?
The magazine, referring to the Spanish-speaking pediatric, indexed in major international databases: Journal of Gastrointestinal and Liver Disease ; 15 1: Garmendia 2S. Previous article Next article. Dina J, et al. The Journal is published both in Spanish and English.
Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Liver involvement in Langehan’s cell histiocytosis. Case report Histiocitosis de Langerhans: SJR uses a langerhhans algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact.
This form of presentation is rare, and seems to be a variant of congenital dd reticulohistiocytosis.
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Subscribe to our Newsletter. N Engl J Med,pp. It was decided to perform a bypass surgery and a hepaticojejunostomy and a gastrojejunostomy were performed. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years.
The disease prognosis and its response to treatment is better in the single system form, particularly with bone involvement, and much worse in the multi-system form, especially if several risk organs are involved liver, histiocitoiss, bone marrow and lung. Pulmonary Langerhans cell histiocytosis: There is no standard therapy in adults due to the low number of existing cases, histocitosis treatment will depend on the degree of involvement.
In our series of cases there was no gender difference and the mean age at presentation was 33 months. The main pathological finding is the presence histicoitosis an accumulation of Langerhans histiocytes, langerhan have distinctive nuclei features a central “coffee bean” shaped folding, fine chromatin, and oval shaped nuclei that distinguishes them from conventional histiocytes.
In the course of the disease, pruritic erythematic lesions with papules appeared on the skin of the patient’s torso. In the year has been indexed in the Medlinedatabase, and has become a vehicle for expressing the most current Spanish medicine and modern. It was informed a cholestasis due to long term obstruction of large biliary ducts.
Histiocytosis; Langerhans cells; Pediatrics. Manuscripts will be submitted electronically using the following web site: